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1

Review: The Pharmacology of Dobutamine

Ruffolo, Robert R.

Journal:

The American Journal of the Medical Sciences

Year:

1987

Language:

english

File:

PDF, 4.74 MB

english, 1987

2

Drug Discovery in the Next Millennium

Ohlstein, Eliot H., Ruffolo Jr, Robert R., Elliott, John D.

Journal:

Annual Review of Pharmacology

Year:

2000

Language:

english

File:

PDF, 114 KB

english, 2000

3

New concepts in α-adrenoceptor pharmacology

Robert R. Ruffolo Jr., J. Paul Hieble

Journal:

Pharmacological Research

Year:

1995

Language:

english

File:

PDF, 161 KB

english, 1995

4

Stereochemical studies of adrenergic drugs. Optically active derivatives of imidazolines

Miller, Duane D., Hsu, Fu-Lian, Ruffolo, Robert R., Patil, Popat N.

Journal:

Journal of Medicinal Chemistry

Year:

1976

Language:

english

File:

PDF, 336 KB

english, 1976

5

Progress in Drug Research / Fortschritte der Arzneimittelforschung / Progrès des recherches pharmaceutiques || Pharmacology of synthetic organic selenium compounds

Parnham, Michael J., Graf, Erich, Kolb, Vera M., Seth, Renu, Sinha, Shradha, Ruffolo, Robert R., Hieble, J. Paul, Brooks, David P., Feuerstein, Giora Z., Nichols, Andrew J., De Benedetti, P. G., Jucke

Year:

1991

Language:

english

File:

PDF, 3.67 MB

english, 1991

6

Disease-modifying effects of phosphocitrate and phosphocitrate-β-ethyl ester on partial meniscectomy-induced osteoarthritis

Sun, Yubo, Haines, Nikkole, Roberts, Andrea, Ruffolo, Michael, Mauerhan, David R., Mihalko, Kim L., Ingram, Jane, Cox, Michael, Hanley, Edward N.

Journal:

BMC Musculoskeletal Disorders

Year:

2015

Language:

english

File:

PDF, 3.81 MB

english, 2015

7

Endothelin receptors: Receptor classification, novel receptor antagonists, and potential therapeutic targets

Eliot H. Ohlstein, John D. Elliott, Giora Z. Feuerstein, Robert R. Ruffolo Jr.

Journal:

Medicinal Research Reviews

Year:

1996

Language:

english

File:

PDF, 1.79 MB

english, 1996

8

The interaction of the enantiomers of carvedilol with α1- and β1-adrenoceptors

Andrew J. Nichols, Anthony C. Sulpizio, Daryl J. Ashton, J. Paul Hieble, Robert R. Ruffolo Jr

Journal:

Year:

1989

Language:

english

File:

PDF, 596 KB

english, 1989

9

Characterization of the hemodynamic activities of fenoldopam and its enantiomers in the dog

Lewis B. Kinter, Eugene Horner, William A. Mann, Dr. Robert R. Ruffolo Jr., Joseph Weinstock

Journal:

Year:

1990

Language:

english

File:

PDF, 680 KB

english, 1990

10

Effects of catechol ring fluorination on cardiovascular and renal activities of fenoldopam enantiomers

Lewis B. Kinter, William A. Mann, Joseph Weinstock, Robert R. Ruffolo Jr.

Journal:

Year:

1994

Language:

english

File:

PDF, 971 KB

english, 1994

11

α-adrenoceptors: Recent developments

Robert R. Ruffolo Jr., Jeffrey M. Stadel, J. Paul Hieble

Journal:

Medicinal Research Reviews

Year:

1994

Language:

english

File:

PDF, 3.19 MB

english, 1994

12

Apoptosis: a potential target for discovering novel therapies for cardiovascular diseases

Tian-Li Yue, Eliot H Ohlstein, Robert R Ruffolo Jr

Journal:

Current Opinion in Chemical Biology

Year:

1999

Language:

english

File:

PDF, 755 KB

english, 1999

13

Chirality in α- and β-adrenoceptor agonists and antagonists

Robert R. Ruffolo Jr.

Journal:

Year:

1991

Language:

english

File:

PDF, 2.36 MB

english, 1991

14

Carvedilol: A Novel Cardiovascular Drug with Multiple Actions

Robert R. Ruffolo Jr., Duane A. Boyle, David P. Brooks, Giora Z. Feuerstein, Robert P. Venuti, Mary Ann Lukas, George Poste

Journal:

Cardiovascular Therapeutics

Year:

1992

Language:

english

File:

PDF, 2.39 MB

english, 1992

15

Carvedilol: A Novel Multiple Action Antihypertensive Drug that Provides Major Organ Protection

Giora Feuerstein, Tian-Li Yue, XinLiang Ma, Robert Ruffolo Jr.

Journal:

Cardiovascular Therapeutics

Year:

1994

Language:

english

File:

PDF, 1.25 MB

english, 1994

16

Effects of a hydroxylated metabolite of the β-adrenoreceptor antagonist, carvedilol, on post-ischaemic splanchnic tissue injury

Theodore A Christopher, Bernard L Lopez, Xin-Liang Ma, Giora Z Feuerstein, Robert R Ruffolo Jr, Tian-Li Yue

Journal:

British Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 326 KB

english, 1998

17

Congestive Heart Failure and Genomic Medicine: A Look into the 21st Century

Giora Z. Feuerstein, Robert R. Ruffolo

Journal:

Cardiovascular Drugs and Therapy

Year:

1997

Language:

english

File:

PDF, 217 KB

english, 1997

18

Pharmacology of Carvedilol: Rationale for Use in Hypertension, Coronary Artery Disease, and Congestive Heart Failure

Robert R. Ruffolo, Giora Z. Feuerstein

Journal:

Cardiovascular Drugs and Therapy

Year:

1997

Language:

english

File:

PDF, 185 KB

english, 1997

19

Antioxidant Action of Carvedilol: A Potential Role in Treatment of Heart Failure

Tian-Li Yue, Robert R. Ruffolo, Giora Feuerstein

Journal:

Heart Failure Reviews

Year:

1999

Language:

english

File:

PDF, 221 KB

english, 1999

20

Carvedilol case history: the discovery and development of the first β-blocker for the treatment of congestive heart failure

Ruffolo, Robert R, Feuerstein, Giora Z

Journal:

Expert Opinion on Drug Discovery

Year:

2006

Language:

english

File:

PDF, 91 KB

english, 2006

21

Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs

David P. Brooks, Todd A. Fredrickson, Joseph Weinstock, Robert R. Ruffolo, Richard M. Edwards, Miklos Gellai

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1992

Language:

english

File:

PDF, 614 KB

english, 1992

22

Pharmacologic differentiation between pre- and postjunctional α2-adrenoceptors by SK & F 104078

Robert R. Ruffolo, Anthony C. Sulpizio, Andrew J. Nichols, Robert M. DeMarinis, Paul Hieble

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1987

Language:

english

File:

PDF, 463 KB

english, 1987

23

Adrenoceptor-mediated effects of optically active catecholimidazolines in pithed rat

Robert R. Ruffolo, Popat N. Patil, Duane D. Miller

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1983

Language:

english

File:

PDF, 734 KB

english, 1983

24

Interactions of three inotropic agents, ASL-7022, dobutamine and dopamine, with α- and β-adrenoceptors in vitro

Robert R. Ruffolo, Karen Messick, J. S. Horng

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1984

Language:

english

File:

PDF, 1.15 MB

english, 1984

25

Interactions of the enantiomers of 3-O-methyldobutamine with α- and β-adrenoceptors in vitro

Robert R. Ruffolo, Karen Messick, J. S. Horng

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1985

Language:

english

File:

PDF, 977 KB

english, 1985

26

Blockade of postjunctional vascularalpha1- andalpha2-adrenoceptors in pithed rat by the enantiomers of WB-4101

Robert R. Ruffolo, Wendel L. Nelson, Emily L. Yaden

Journal:

Naunyn-Schmiedeberg's Archives of Pharmacology

Year:

1983

Language:

english

File:

PDF, 532 KB

english, 1983

27

Effect of chronic ethanol consumption on the pancreas of the hamster

Robert E. Weesner, John J. Ruffolo, Richard F. Murphy, Hosoon P. Dincsoy, Charles L. Mendenhall

Journal:

Digestive Diseases and Sciences

Year:

1985

Language:

english

File:

PDF, 2.61 MB

english, 1985

28

Gallbladder ejection fraction and its relationship to sphincter of Oddi dysfunction

Thomas A. Ruffolo, Stuart Sherman, Glen A. Lehman, Robert H. Hawes

Journal:

Digestive Diseases and Sciences

Year:

1994

Language:

english

File:

PDF, 323 KB

english, 1994

29

Antinociceptive activity of N-(4-hydroxyphenacetyl)-4-aminoclonidine, a novel analog of clonidine: Role of opioid receptors and alpha-adrenoceptors

Martin D. Hynes, Daphne Atlas, Robert R. Ruffolo Jr.

Journal:

Pharmacology Biochemistry and Behavior

Year:

1983

Language:

english

File:

PDF, 327 KB

english, 1983

30

Distribution and function of peripheral α-adrenoceptors in the cardiovascular system

Robert R. Ruffolo Jr.

Journal:

Pharmacology Biochemistry and Behavior

Year:

1985

Language:

english

File:

PDF, 842 KB

english, 1985

31

α-Adrenoceptors

Robert R. Ruffolo Jr., J.Paul Hieble

Journal:

Pharmacology & Therapeutics

Year:

1994

Language:

english

File:

PDF, 6.00 MB

english, 1994

32

Behaviors of youth involved in the child welfare system

Andrew Grogan-Kaylor, Mary C. Ruffolo, Robert M. Ortega, Jenell Clarke

Journal:

Child Abuse & Neglect

Year:

2008

Language:

english

File:

PDF, 180 KB

english, 2008

33

Protective Effects of Carvedilol in the Myocardium

Giora Z Feuerstein MD, Antoine Bril PhD, Robert R Ruffolo Jr, PhD

Journal:

The American Journal of Cardiology

Year:

1997

Language:

english

File:

PDF, 81 KB

english, 1997

34

Comparison of bisoprolol and carvedilol cardioprotection in a rabbit ischemia and reperfusion model

Feng Gao, Jun Chen, Bernard L Lopez, Theodore A Christopher, Juanli Gu, Paul Lysko, Robert R Ruffolo Jr., Eliot H Ohlstein, Xin L Ma, Tian-Li Yue

Journal:

European Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 355 KB

english, 2000

35

Comparison of metoprolol and carvedilol pharmacology and cardioprotection in rabbit ischemia and reperfusion model

Giora Feuerstein, Gao-Lin Liu, Tian-Li Yue, H-Y Cheng, J.Paul Hieble, Jonathan R.S Arch, Robert R Ruffolo Jr., X.-L Ma

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 340 KB

english, 1998

36

SB 211475, a metabolite of carvedilol, reduces infarct size after myocardial ischemic and reperfusion injury in rabbits

Harald Brunvand, Gaolin Liu, Xin-Liang Ma, Tian-Li Yue, Robert R Ruffolo Jr., Giora Z Feuerstein

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 233 KB

english, 1998

37

Effects of α1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity

J.Paul Hieble, David C Kolpak, Gerald P McCafferty, Robert R Ruffolo Jr., Rodolfo Testa, Amedeo Leonardi

Journal:

European Journal of Pharmacology

Year:

1999

Language:

english

File:

PDF, 302 KB

english, 1999

38

Novel mechanisms in the treatment of heart failure: Inhibition of oxygen radicals and apoptosis by carvedilol

Giora Feuerstein, Tian-Li Yue, Xinliang Ma, Robert R. Ruffolo

Journal:

Progress in Cardiovascular Diseases

Year:

1998

Language:

english

File:

PDF, 1.02 MB

english, 1998

39

Apoptosis and Congestive Heart Failure

Giora Feuerstein, Robert R Ruffolo Jr., Tian-Li Yue

Journal:

Trends in Cardiovascular Medicine

Year:

1997

Language:

english

File:

PDF, 2.02 MB

english, 1997

40

L 1 - IMIDAZOLINE RECEPTORS: HISTORICAL PERSPECTIVE

J. Paul Hieble, Robert R. Ruffolo Jr.

Journal:

Fundamental & Clinical Pharmacology

Year:

1992

Language:

english

File:

PDF, 634 KB

english, 1992

41

Importance of receptor regulation in the pathophysiology and therapy of congestive heart failure

Robert R. Ruffolo Jr., Gregory A. Kopia

Journal:

The American Journal of Medicine

Year:

1986

Language:

english

File:

PDF, 648 KB

english, 1986

42

Biochemical correlates for the pharmacological effects of L(+)-Isomers and β-desoxy-sympathomimetic amines

Robert R. Ruffolo Jr., Duane D. Miller, Popat N. Patil

Journal:

Biochemical Pharmacology

Year:

1976

Language:

english

File:

PDF, 669 KB

english, 1976

43

Properties of 8,9-dichloro-2,3,4,5-tetrahydro-1H- 2-benzazepine, an inhibitor of norepinephrine N-methyltransferase

Ray W. Fuller, Susan Hemrick-Luecke, Richard E. Toomey, Jong-Sin Horng, Robert R. Ruffolo Jr., Bryan B. Molloy

Journal:

Biochemical Pharmacology

Year:

1981

Language:

english

File:

PDF, 777 KB

english, 1981

44

Receptor interactions of imidazolines influence of ionization constant on the diffusion of clonidine and a series of structurally related imidazolidines into and out of the central nervous system

Robert R. Ruffolo Jr., Emily L. Yaden, John S. Ward

Journal:

European Journal of Pharmacology

Year:

1982

Language:

english

File:

PDF, 670 KB

english, 1982

45

Selective α2-adrenoceptor agonist activity of the novel inotropic agent, ASL-7022: Comparison with dobutamine

Robert R. Ruffolo Jr., Emily L. Yaden

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 281 KB

english, 1983

46

Differences in the applicability of the Easson-Stedman hypothesis to the α1- and α2-adrenergic effects of phenethylamines and imidazolines

Robert R. Ruffolo Jr., Peter J. Rice, Popat N. Patil, Akihiko Hamada, Duane D. Miller

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 352 KB

english, 1983

47

Relative potency of LY141865 at dopamine DA2 and histamine H2 receptors

Robert R. Ruffolo Jr., Carl J. Shaar

Journal:

European Journal of Pharmacology

Year:

1983

Language:

english

File:

PDF, 133 KB

english, 1983

48

Systemic hemodynamic effects of dopamine, (±)-dobutamine and the (+)- and (−)-enantiomers of dobutamine in anesthetized normotensive rats

Robert R. Ruffolo Jr., Karen Messick

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 672 KB

english, 1985

49

Relationship between α2-adrenoceptor occupancy and response for B-HT 933 in canine saphenous vein

Robert R. Ruffolo Jr., Robert L. Zeid

Journal:

European Journal of Pharmacology

Year:

1985

Language:

english

File:

PDF, 361 KB

english, 1985

50

The relationship between alterations in α1-adrenoceptor reserve by phenoxybenzamine and benextramine and the sensitivity of cirazoline-induced pressor responses to inhibition by nifedipine

Andrew J. Nichols, Robert R. Ruffolo Jr.

Journal:

European Journal of Pharmacology

Year:

1986

Language:

english

File:

PDF, 379 KB

english, 1986